Home Team Results
| Date | Home | | Away | | Result |
| 2021/12/01 | Southampton | (2) 2 | Leicester | (1) 2 |
D |
| 2021/11/27 | Liverpool | (3) 4 | Southampton | (0) 0 |
L |
| 2021/11/20 | Norwich | (1) 2 | Southampton | (1) 1 |
L |
| 2021/11/05 | Southampton | (1) 1 | Aston Villa | (0) 0 |
W |
| 2021/10/30 | Watford | (0) 0 | Southampton | (1) 1 |
W |
| 2021/10/23 | Southampton | (1) 2 | Burnley | (1) 2 |
D |
| 2021/10/16 | Southampton | (0) 1 | Leeds | (0) 0 |
W |
| 2021/10/02 | Chelsea | (1) 3 | Southampton | (0) 1 |
L |
| 2021/09/26 | Southampton | (0) 0 | Wolves | (0) 1 |
L |
| 2021/09/18 | Man City | (0) 0 | Southampton | (0) 0 |
D |
| 2021/09/11 | Southampton | (0) 0 | West Ham | (0) 0 |
D |
| 2021/08/28 | Newcastle | (0) 2 | Southampton | (0) 2 |
D |
| 2021/08/22 | Southampton | (1) 1 | Man United | (0) 1 |
D |
| 2021/08/14 | Everton | (0) 3 | Southampton | (1) 1 |
L |